Martin Karplus, a theoretical chemist, developed the standard methods for investigating molecules and their interactions. Molecules are essential to life and his research described their function and thus opened up enormous possibilities in medicine and pharmacology. Martin Karplus and fellow research scholars Michael Levitt and Arieh Warshel were awarded the 2013 Nobel Prize in Chemistry for their theoretical and practical computer based research. Today’s application of molecular diagnosis would not be possible without this ground-breaking work. Karplus played a decisive role in the development of theoretical computer-aided chemistry using molecular-mechanical and quantum -mechanical methods. His “Karplus Equation” is now in widespread everyday use for calculating the structures of molecules in solution. He was the first to carry out the molecular-dynamic simulation of a protein and by so doing pioneered bio-molecular simulation, something that he himself regards as his most important scientific achievement. In addition he has more than 850 publications to his name, many of them ground-breaking in their content. Martin Karplus is an extraordinarily creative and productive scientist.


Martin Karplus

Martin Karplus was born in Vienna on the 15th of March 1930 and, in 1938, was forced into exile by the Nazis. The film portrays Martin Karplus on location at his scientific work in Harvard and Strasbourg. It attempts to portray and understand the results of his research while projecting forward to his potential impact on medicine and pharmacology. The film crew accompanies Martin Karplus to Vienna where, in the spring of 2015, on the 650th anniversary of the University, he will be presented with an honorary doctorate. As a part of this tribute an exhibition of his photography will be held. And along with this he seeks to be convinced that in Vienna, anti-Semitism is finally in retreat.



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